DEFEATING PATHOGEN DRUG RESISTANCE: GUIDANCE FROM EVOLUTIONARY THEORY
نویسندگان
چکیده
منابع مشابه
Evolutionary dynamics of pathogen resistance and tolerance.
Host organisms can respond to the threat of disease either through resistance defenses (which inhibit or limit infection) or through tolerance strategies (which do not limit infection, but reduce or offset its fitness consequences). Here we show that resistance and tolerance can have fundamentally different evolutionary outcomes, even when they have equivalent short-term benefit for the host. A...
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ژورنال
عنوان ژورنال: Evolution
سال: 2008
ISSN: 0014-3820,1558-5646
DOI: 10.1111/j.1558-5646.2008.00525.x